MKI67 and neuroendocrine neoplasm: Additionally, the nodule was classified as non-functional based on a negative assessment of 5-hydroxy-indolacetic acid and chromogranin A. The patient was submitted to a pancreatic uncinectomy and the histopathologic sample evidenced a localized grade 2 well-differentiated neuroendocrine tumor of the pancreas with 0.9×0.7cm, Ki-67 of 4.7%, glucose transport proteins 1 (GLUT1) negative by immunohistochemistry, pT1pNxpM0 (The American Joint Committee—AJCC 8th edition) (Fig. 3).