Finally, SFTPA1, PLXNB3, BIRC5, CBLC, and ACVRL1 were screened out based on the intersection between the top 10 differentially expressed genes in lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) (Supplementary Fig. 1a). The gene discussed is ACVRL1; the disease is lung adenocarcinoma.