CCL3 and asthma: However, the levels of IL-17, MIP-1α, MIP-2 showed no significant difference between the three intervention groups, which, respectively, inoculated with CS-RC nanoparticles, CS nanoparticles, rIL-17RC proteins, whereas mice from the three groups demonstrated a significant reduction of IL-17, MIP-1α, MIP-2 in comparison with mice from asthma group (all P < 0.05).