CXCL12 and myocardial infarction: Although there are other studies that show reduced plasmatic levels of SDF-1α in the acute settings of MI in relation to the increased binding of SDF-1 at its receptors CXCR4 and CXCR7 on the reactive blood cells [27], the precise plasmatic levels may depend upon situation on local concentration, duration, and time period after MI [28].