In summary, these data suggest a functional link among RBFOX2, GOLIM4, and RAB26, where RBFOX2 recognizes GGAA motif to generate a long isoform of GOLIM4‐L and jointly regulate the tumorigenesis of NPC cells through vesicle transportation, involving the recruitment of RAB26 to Golgi with a stronger binding to GOLIM4‐L (Figure 8). This evidence concerns the gene GOLIM4 and nasopharyngeal carcinoma.