Among them, some studies have found that the level of CACYBP/SIP in gastric cancer cells is positively correlated with cancer differentiation, and we have also found that the high expression of CACYBP/SIP can inhibit the proliferation and invasion ability of gastric cancer cells and inhibit the growth of tumor cells in vitro (NING et al., 2007). The gene discussed is CACYBP; the disease is gastric cancer.