The results showed that the expression of CORO1C was significantly related to the histological type (χ2 = 7.6419, p = 0.006), lymph node metastases (χ2 = 19.1615, p < 0.001), distant metastases (χ2 = 9.5623, p = 0.002), AJCC stage (χ2 = 17.7192, p = 0.001), venous invasion (χ2 = 22.1337, p < 0.001), and perineural invasion (χ2 = 21.1141, p < 0.001). Here, CORO1C is linked to metastatic malignant neoplasm in the lymph nodes.