There are reports that BAP31 knockdown reduces expression level of TGF-β1, MMP-2, MMP-9, ROCK1, α-SMA, Vimentin and N-cadherin in cervical cancer (Wang et al., 2019), and BAP31 affects F-actin distribution to promote migration and invasion of lung cancer cells (Wang et al., 2020). This evidence concerns the gene MMP2 and lung carcinoma.