REN and Hypomagnesemia: As shown in Table 2, all GS patients (Male/Female = 9/1, age 33.4 ± 7.8 years old) were normotensive with renal Na+ and Cl− wasting and secondary hyperreninemia (plasma renin activity, PRA 28.9 ± 14.4 ng/mL/h) but normal to high plasma aldosterone concentration (PAC) (229.4 ± 69.6 pg/mL), chronic hypokalemia (K+, 2.34 ± 0.45 mmol/L) with higher urinary K+ excretion (transtubular potassium gradient, 13.46 ± 10.91), metabolic alkalosis (HCO3−, 28.7 ± 3.9 mmol/L), hypomagnesemia (Mg2+ 0.63 ± 0.07 mmol/L), and hypocalciuria (Ca2+/Creatinine 0.07 ± 0.06 mmol/mmol).