LCN2 and ischemic stroke: Plasma level of LCN2 was found to be significantly elevated in patients with ischemic stroke, especially in the early stages, and to be a risk factor for unfavorable modified Rankin scale scores, the occurrence of post-stroke infections and cardiovascular mortality (Anwaar et al., 1998; Falke et al., 2000; Hochmeister et al., 2016).