Meanwhile, crosstalk between M2-like macrophages and PCs in glioblastoma (GBM) promotes PC recruitment and upregulates the expression of the proangiogenic ECM component periostin deposition in PCs through the CECR1–PDGF-B–PDGFR-β signaling pathway (Zhu et al., 2017). This evidence concerns the gene PDGFB and glioblastoma.