Target sequencing performed on ccfDNA and tumor FFPE tissue with the 92-gene custom panel identified 16 non-synonymous, somatic genetic alterations not detected in the normal cells in the ccfDNA and 8 in the tumor DNA (Table 2), including ARID1A deletion (I1485Rfs∗19, AF: 32.6%) and mutation (p. A1487V, AF: 33.2%) and a mutation in FGFR2 gene (p.G272R, AF:19%). This evidence concerns the gene ARID1A and neoplasm.