Liu et al. (2020) recently reported that 1 to 2% of non-severe and 17% of severe patients with COVID-19 had pancreatic injury, which is consistent with our notion that specific ACE2 expression in the pancreas results in this phenotype after SARS-CoV-2 infection. Therefore, the highly expressed ACE2 in pancreatic islets may increase the risk of SARS-COV-2 infection and damage (Liu et al., 2020). The gene discussed is ACE2; the disease is COVID-19.