In colon cancer cells, lncRNA Xist (Sun N.N. et al., 2018), which functions as a ceRNA by binding to miR-34a and positively modulates WNT1 expression, has a crucial function in colon cancer progression via the miR-34a/WNT1 axis to activate the Wnt/β-catenin signaling pathway. The gene discussed is WNT1; the disease is malignant colon neoplasm.