And other ceRNA regulatory networks have also been shown to contribute to the progression of Osteoarthritis, such as lncRNA Xist/miR-376c-5p/OPN signaling pathway (Li et al., 2020b), lncRNA Xist/miR-142-5p/SGTB signaling pathway (Ghaderian et al., 2020), lncRNA Xist/miR-149-5p/DNMT3A signaling pathway (Liu et al., 2020e), and lncRNA Xist/miR-675-3p/GNG5 signaling pathway (Shen X.F. et al., 2020). Here, XIST is linked to osteoarthritis.