Similarly, Du Y. et al. (2020) showed that lncRNA Xist, which was significantly upregulated in hydrogen peroxide (H2O2)-induced AD mice models and in H2O2-treated N2a cells, is involved in Alzheimer’s disease development though positively regulating BACE1 expression by interacting with miR-124. The gene discussed is XIST; the disease is Alzheimer disease.