In addition, lncRNA Xist mediates glioma progression, tumorigenesis, metastasis, proliferation, apoptosis, and glucose metabolism by positively regulating Bcl-2, FOXC1, ZO-2, Rac1, ASCT2, SLC1A5, SOX4, Smurf1, and IRS1 by functioning as a ceRNA of miR-204-5p, miR-137, miR-133a, miR-27a, and miR-126 (Wang Z. et al., 2017; Yu H. et al., 2017; Cheng Z.H. et al., 2020; Luo C.X. et al., 2020; Shen J. et al., 2020; Sun Y. et al., 2020; Yao et al., 2020; Zhao Q. et al., 2020). Here, XIST is linked to central nervous system cancer.