Sato et al. (2018) also supported the role of erastin by showing that short erastin pretreatment was sufficient to synergize with cisplatin to kill tumor cell death. Similarly, Lei et al. (2020) demonstrated that ferroptosis inducers endowed radio-resistant tumor cells with radiation sensitivity via inactivation of SLC7A11 (a protein controlling the transport of cystine and glutamate), leading to ferroptotic cell death. This evidence concerns the gene SLC7A11 and neoplasm.