CAV1 and cutaneous squamous cell carcinoma: For example, Yu et al. found that CAV1 can promote hepatocellular carcinoma cell progression and metastasis through the Wnt/β-Catenin pathway (Yu et al., 2014), whereas Trimmer et al. demonstrated that CAV1 suppressed tumor growth and metastasis in a murine model of cutaneous squamous cell carcinoma through modulation of MAPK/AP-1 activation (Trimmer et al., 2013).