The colors from yellow to red represent small to large degree values, respectively, and according to the degree values, the key nodes, which are epidermal growth factor receptor (EGFR), ESR1, SRC, ERBB2, MTOR, MCL1, matrix metalloproteinase 2 (MMP2), MMP9, KDR, and JAK2, were selected for interactions with NSCLC. The gene discussed is MMP2; the disease is non-small cell lung carcinoma.