In addition, some family members of SERPING1, including SERPINA3, SERPINA4, SERPINA7, and SERPINC1, were also found to be dysregulated in T2D patients through glycoproteomics in our study, which were involved in platelet degranulation and peptidase inhibitor pathways (Figure 6A). The gene discussed is LAP3; the disease is type 2 diabetes mellitus.