CALCA and cutaneous leishmaniasis: RANTES/CCL5, together with KC/CXCL1 and MIP-2/CXCL2 (Ohmori and Hamilton, 1994; Lebovic et al., 2001) participate in neutrophil, monocyte, and lymphocyte recruitment to inflammatory focus and interfere in the persistence of cutaneous leishmaniasis lesions (Teixeira et al., 2005; Costa-Silva et al., 2014).