NLRP3 and papillary renal cell carcinoma: A similar behavior was seen in renal adenocarcinoma cells (Figures 5D, E); NLRP3 was overexpressed after exposure to sunitinib compared to untreated cells (3.3 ± 0.26 vs 1 ± 0.23, (fold of control) p<0.001); lower levels of NLRP3 after co-incubation with polydatin were seen (2.4 ± 0.16 and 1.6 ± 0.21 for 100 and 200 μM, as fold of control) p<0.001 (Figure 5D).