MYD88 and cancer: Similarly, Myd88 expression was enhanced after exposure to sunitinib compared to untreated cancer cells (2.33 ± 0.16 vs 1 ± 0.14, (fold of control) p<0.001); lower levels of Myd88 after co-incubation with polydatin were also seen (1.91 ± 0.27 and 1.86 ± 0.27 for 100 and 200 μM, as fold of control) p<0.001 vs sunitinib-exposed cells (Figure 5E).