CD4+ and CD8+ memory T cells targeting the mutated KRASG12D and KRASG12V variants respectively in the peripheral blood of cancer patients were conformed and isolated, suggesting that we can detect memory T cells targeting distinct or common somatic mutations in the peripheral blood of epithelial cancer patients and can hopefully use them to develop efficient individualized T cell-based cancer immunotherapy among a variety of patients (70). Here, CD8A is linked to cancer.