NUF2 and non-small cell lung carcinoma: As there is no current research on NUF2 methylation, and our study could not perform experimental research for probing potential methylation mechanisms of NUF2 in NSCLC, further research was needed to explore the mechanism between NUF2 expression and NUF2 methylation in NSCLC, and whether the different levels of NUF2 methylation have different effects on the occurrence, development and prognosis between LUAD and LUSC, and to find the cause of the difference of NUF2 methylation between them.