ENO2 and adenocarcinoma: In the cohort of patients with adenocarcinoma presenting as GGO, log rank tests showed that elevated CEA(P<0.0001), CYFRA21-1(P=0.021) and CA125(P<0.0001) were associated with worse RFS while elevated serum NSE(P=0.21), CA153(P=0.53) and CA199(P=0.48) were not.