LEPR and coronary artery disorder: Nowaria et al. deduced that APLNR rs11544374 gene polymorphism could represent a predisposition for CAD in the southeast Iranian population [38]. Khaki-Khatibi et al. studied demonstrated that Q223R (rs1137101) SNP of the LEPR gene conveys susceptibility to non-ST elevation myocardial infarction (NSTEMI).