The UMAP from this analysis, from 13.4 thousand cells in Figure 3A consisted of 18 cell clusters with the following annotations derived from marker genes reported by the recent meta-analysis of leukocytes in murine atherosclerosis [18]: 6 Trem2+ Foamy Macrophage clusters (FoamyMac1-6), 1 resident macrophage cluster, 1 inflammatory macrophage cluster, 1 macrophage/monocyte mixed cluster, 3 monocyte and dendritic cell mixed clusters (mono/DC1-3), 1 neutrophil cluster, 1 CD8+ T cell cluster, 1 IL17+ T cell cluster, 1 B cell cluster, and 2 other stromal clusters (Figure 3A). The gene discussed is CD8A; the disease is atherosclerosis.