On the other hand, in individuals without hypoalphalipoproteinemia, the rs17574 minor allele was related with 25% lower risk of IR (OR = 0.75, Padditive = 0.049), approximately 40% higher risk of high non-HDL-C (OR = 1.47, Pheterozygote = 0.023; OR = 1.45, Pco–dominant1 = 0.033) and high apoB (OR = 1.44, Pheterozygote = 0.043; Table 2). This evidence concerns the gene APOB and hypoalphalipoproteinemia.