TBCE and metabolic dysfunction-associated steatohepatitis: While a first study likely mixed resident KCs and recruited-temporary macrophages (LAMs) leading to the conclusion that KCs were activated in NASH (75), another recent study where NASH was induced in mice by feeding a methionine and choline deficient diet (MCD diet), did report increased expression of pro-inflammatory genes in resident KCs after 6 weeks of feeding (23).