IL33 and inflammation: As the alarmin IL-33 represents a well-established promotor of the bone marrow-to-lung recruitment of ILC2s under inflammatory conditions and also serves as a key activating cytokine for pulmonary ILC2 pools (125, 126), its antibody-mediated blockade can be expected to relevantly dampen the local involvement of ILC2s in the induction or maintenance of lung inflammation.