CCR4 and asthma: Interestingly, molecular docking studies indicated that the anti-malarial hydroxychloroquine, whose potential benefit for patients suffering from COVID-19 disease had been under intensive debate (151), was able to interact with the active site of CCR4, implicating that an inhibitory effect on CCR4 signaling might, at least partly, underly the reported therapeutic and immunomodulatory capacity of this drug in the clinical context of asthma (152, 153).