Patients with cardiovascular failure and hypotension requiring intravenous pressors showed lower IL-7 levels later in their COVID-19 trajectory, while CXCL5, IL-12, and ANGPT-1 levels were depressed early during the course of infection (Figure 7A; Supplemental Figure 1A and Supplemental Material 2). The gene discussed is ANGPT1; the disease is COVID-19.