AGT and pneumonia: SARS-CoV-2 binding to ACE2, and Ang II-induced activation of AT1R, and activation of complement pathways by SARS-CoV-2 may induce assembly of the NLRP3 inflammasome (33–35), which contributes to the onset of cytokine storm, pneumonia, ARDS, thrombosis, DIC, and other types of organ dysfunction (35–37).