In trial to assess improvement in therapeutic outcomes by optimizing platelet inhibition with Prasugrel–Thrombolysis in myocardial infarction 38 trial, ACS PCI patients with ATP Binding Cassette Subfamily B Member 1 (ABCB1) T-allele homozygotes had adverse cardiovascular events like recurrent stroke and MI (91). Here, ABCB1 is linked to Stroke.