ADA2 and Diamond-Blackfan anemia: Morgado-Palacin et al. (2015) previously demonstrated reduced ribosomal protein gene expression in Rpl11 mutant mice. We also found a global decrease in ribosomal protein gene expression in proerythroblasts. However, the effect of CECR1 mutations in DBA pathogenesis should be investigated in detail if there is a direct relationship with ribosome biogenesis.