CD163 and portal hypertension: Macrophage activation, as measured by sCD163, is associated with liver fibrosis and cirrhosis, liver disease severity (Child-Pugh- and MELD scores), and portal hypertension (Holland-Fischer et al., 2011; Gronbaek et al., 2012; Rode et al., 2013; Kazankov et al., 2014, 2015, 2016; Grønbæk et al., 2020).