Of these up-regulated S-NO proteins, three proteins, myelin-oligodendrocyte glycoprotein (MOG), glutathione s-transferase Mu 3 (GSTM3), and four and a half LIM domains protein 1 (FHL1), were found at a higher level in AD compared to either MCI or Ctrl cases (Wijasa et al., 2020). This evidence concerns the gene GSTM3 and Alzheimer disease.