The results of our study confirm findings of the STAtins Reduce Thrombophilia (START) trial, which concluded that one-month treatment with rosuvastatin 20 mg daily in patients with prior VTE reduced the plasma levels of coagulation factors VII:C, FVIII:C, FXI:C and von Willebrand factor (vWF):Ag in comparison with non-statin users [17]. This evidence concerns the gene RENBP and Rare hereditary thrombophilia.