Except for rs897200, the STAT4 rs3821236 (Allele: OR 1.42, p = 0.014; Homozygote: OR 1.42, p = 0.014; Heterozygote: OR 1.42, p = 0.014; Dominant: OR 1.42, p = 0.014; Log-additive: OR 1.42, p = 0.014), rs11893432 (Allele: OR 1.43, p = 0.011; Homozygote: OR 2.03, p = 0.015; Dominant: OR 1.65, p = 0.019; Log-additive: OR 1.44, p = 0.012), rs11889341 (Heterozygote: OR 1.61, p = 0.025; Dominant: OR 1.49, p = 0.036) and rs7574865 (Heterozygote: OR 1.62, p = 0.023) were all significantly associated with T2D risk among non-drinking participants. The gene discussed is STAT4; the disease is type 2 diabetes mellitus.