However, if anything, one would expect free PlGF levels to be further decreased in women with HELLP syndrome at a later GA because free PlGF levels start declining from 29 to 32 weeks’ gestation until the end of pregnancy.14 Lastly, it should be taken into account that the pregnancies of women defined as no preeclampsia were not entirely healthy, which might have influenced the interpretation of total PlGF in this population. This evidence concerns the gene PGF and HELLP syndrome.