Interestingly, HLA-B*51:01 was also found significantly associated with AEDs-induced cADRs with OR 2.292, but when we separated the data in each drug category, we found that HLA-B*51:01 was significantly associated with PHT-induced STS/TEN and CBZ-induced DRESS compared to tolerant controls with OR of 6.19 and 7.94, respectively. Here, HLA-B is linked to telomere syndrome.