We analyzed each AEDs separately and found the association of HLA-B*15:02 and PHT-induced SJS/TEN (OR 3.60, 95%CI 1.59–8.15, p = 0.001), and HLA-B*15:02 and CBZ-induced SJS/TEN (OR 141.89, 95%CI 48.14–419.19, p < 0.001). Here, HLA-B is linked to toxic epidermal necrolysis.