While some genes found are known cancer census genes (RAF1, BCL6, STAT3, CCND3, EWSR1, HSP90AB1, LASP1, HSP90AA1, STAT5B, PICALM, NACA, CSF3R, FUS, H3F3B, CALR, MALAT1, LEF1, CXCR4, BIRC3, TPM3, CD79A, HNRNPA2B1, AKT2, SYK, and NUMA1) [32], evidence of aberrated expression of these genes could be a pre-clinical indication for further assessment. This evidence concerns the gene PICALM and cancer.