AKT1 and colorectal carcinoma: Many studies also suggested that abnormal lncRNAs expressions contributed to CRC carcinogenesis through a cascade of regulatory signalling pathways such as autophagy, apoptosis, AMP activated protein kinase (AMPK), epithelial-mesenchymal transition (EMT), mTOR, PI3K/AKT, Wnt/β-catenin, JAK/STAT, MAPK, p53, and Notch [11–15].