The selected six immune factors of component 1, as expected, had significant quantitative higher levels in COVID-19 compared to controls for: IL-2, IFN-γ, IP-10 induced by Spike (p  =  0.0018; p  =  0.0175; p  <  0.0001; respectively), NP Pool1 RANTES (p  =  0.001), NP Pool2 IP-10 (p  =  0.027) and ORF3a IL-2 (p  =  0.039) (Fig. 3; Table 2). The gene discussed is IFNG; the disease is COVID-19.