IP-10 production significantly increased after Spike stimulation in the cohort A of “hospitalized COVID-19-patients enrolled between 1 and 14 days after symptoms onset” (p  =  0.0014) and in the cohort B of “not hospitalized COVID-19-patients” (p  =  0.0002), (Fig. 5A–B). The gene discussed is CXCL10; the disease is COVID-19.