These genes also regulate a number of biological pathways in the progression of cervical lesions, such as the cell cycle, DNA replication, rheumatoid arthritis, the p53 signaling pathway, bladder cancer, complement and coagulation cascades, amoebiasis, cytokine-cytokine receptor interaction, oocyte meiosis, and arachidonic acid metabolism. Here, TP53 is linked to urinary bladder carcinoma.