As shown in the survival maps in Fig. 2a, we observed that high expression of SEC61G was related to a poor OS (overall survival) rate among HNSCC, BRCA (breast invasive carcinoma), LGG (brain lower-grade glioma), and LIHC (liver hepatocellular carcinoma) patients in the TCGA database. This evidence concerns the gene SEC61G and invasive breast carcinoma.