In contrast, in HCT116−/− cells harboring truncated p53, no significant difference in cell survival was found even with increased doses (43 ± 2% at a mazF:mazE co-infection ratio of 10:1, compared to 43 ± 2.8% at a ratio of 1:0.5, at an MOI of 3.75). Here, TP53 is linked to coinfection.