Next, we used EL4, a T lymphoma cell line from C57BL/6J mice, as a donor of mouse exosomal PD-1 (Exo-mPD-1, shown as shControl in Fig. 2C) and generated its PD-1-knockdown clone as a control (Exo-mCon, shown as shmPD-1 in Fig. 2C). The gene discussed is PDCD1; the disease is lymphoma.