Correlating the expression of each activator of actin polymerization individually with FLT3 pathway gene expression showed a moderate positive correlation for WAVE2/PFN1/ARP2 in FLT3-ITD and FLT3 WT de novo AML patients (Fig. S3A–C), but no correlation was observed between N-WASP and FLT3 pathway gene expression (Fig. S3D). Here, FLT3 is linked to acute myeloid leukemia.