Because Rgs4, Akt and mTOR are all linked to several human diseases such as schizophrenia and Parkinson25–27,58 and given the new insights that this work provided strongly associating the three in neurodevelopment and motoneurons outgrowth, it is possible that similar defects intervene in schizophrenia and Parkinson Disease. Here, AKT1 is linked to Parkinson disease.