TP53 and cancer: Moreover, treatment of a range of human cancer cells bearing WT p53 (AGS, A549, CAKI-1, CESS, LS 174T, MDA-MB-175-VII, NCI-H1882, SH-SY5Y, and U-2 OS) with ADH-6 yielded no significant toxicity (Supplementary Fig. 11e).