CT45A1 and osteosarcoma: And surprisingly, we found that the more aberrant expression of CT45A1 was detected in osteosarcoma patients with distant metastasis than those without distant metastasis (Fig. 1F, G) as well as that higher expression of CT45A1 was also detected in osteosarcoma patients with more aggressive clinical pathological grade which suggested us that CT45A1 was related with metastasis of osteosarcoma.