IL1B and rheumatoid arthritis: In this study, we determined the antiproliferative effects of ACRH, QRF and BQ on respective VEGF-induced HUVECs and IL-1β-induced HFLS-RA proliferation after 24 h exposure at the range of concentrations used i.e., 1.56–50 μg/mL for ACRH and QRF, respectively and 0.16–5 μg/mL for BQ.